HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the BYTE_ARRAY_LEN method, the cram_byte_array_len_decode() failed to validate that the amount of data being unpacked matched the size of the output buffer where it was to be stored. Depending on the data series being read, this could result either in a heap or a stack overflow with attacker-controlled bytes. Depending on the data stream this could result either in a heap buffer overflow or a stack overflow. If a user opens a file crafted to exploit this issue it could lead to the program crashing, overwriting of data structures on the heap or stack in ways not expected by the program, or changing the control flow of the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
CVE-2026-31971
This high-severity CVE scores 8.1 under NVD CVSS v3. EPSS exploit probability: 0.3%, top 73% of all CVEs by exploit prediction. GitHub Security Advisory data not yet ingested — confidence will rise once GHSA publishes (typical lag: hours to days for open-source ecosystem CVEs; never for infrastructure-only CVEs).
- High severity, but no confirmed exploitation yet
No vendor fix yet — apply a workaround or compensating control (WAF / firewall / segmentation) and watch for a patch.
- CVSS v3
- 8.1
- EG Score
- 8.1(medium)
- EG Risk
- 41(Track)EG Risk 41/100SSVC: Track
EG Risk is EchelonGraph's 0–100 priority score: it fuses intrinsic severity with real-world exploitation and automatability so you can rank equal-severity CVEs and fix the most dangerous first. Higher = act sooner. Distinct from the 0–10 EG Score (severity).
How it’s computedSeverity81% × 45%Exploitation0% × 40%Automatability30% × 15%Action: Routine — remediate on your standard cadence. - EPSS PROB
- 0%
- EPSS %ILE
- 27%
- KEV
- Not listed
Published
March 18, 2026
Last Modified
June 17, 2026
Advisory Details (2)
Auto-updated Aug 2, 2026Buffer overflow vulnerabilities in HTSlib CRAM decoder · Advisory · samtools/htslib · GitHub
https://github.com/samtools/htslib/security/advisories/GHSA-jvx4-4wq7-6fmhcommit 01cd003b46fa (samtools/htslib)
Patch available: samtools/htslib 1.23.1 (contains commit 01cd003b46fa)
https://github.com/samtools/htslib/commit/01cd003b46fa2ebea4d9be5475b11217eb4c11beAffected Packages
(4 across 4 ecosystems)
Debian:11(1)
| Package | Vulnerable range | Fixed in | Dependents |
|---|---|---|---|
| htslib | 1.11-4 ... 1.22.1+ds2-1 (23 versions) | — | — |
Debian:12(1)
| Package | Vulnerable range | Fixed in | Dependents |
|---|---|---|---|
| htslib | 1.16+ds-3 ... 1.22.1+ds2-1 (17 versions) | — | — |
Debian:13(1)
| Package | Vulnerable range | Fixed in | Dependents |
|---|---|---|---|
| htslib | 1.21+ds-1, 1.22.1+ds-1, 1.22.1+ds-2, 1.22.1+ds2-1 | — | — |
Debian:14(1)
| Package | Vulnerable range | Fixed in | Dependents |
|---|---|---|---|
| htslib | 1.21+ds-1, 1.22.1+ds-1, 1.22.1+ds-2, 1.22.1+ds2-1 | — | — |
Weakness Classification(4)
MITRE Common Weakness Enumeration — the root-cause categories this CVE belongs to.
Data Freshness Timeline
(refreshed 6× in last 7d / 30× in last 30d)
Each row is a source pipeline that fetched or updated this CVE on that date, with what changed. For example, "NVD update" means NVD published or revised its analysis for this CVE; "MITRE cvelistV5" means we ingested or refreshed it from the CNA feed. Most recent first.
- 2026-09-18 19:28 UTCEPSS rescore
- 2026-09-18 19:27 UTCEPSS rescore
- 2026-09-17 19:30 UTCEPSS rescore
- 2026-09-16 14:08 UTCEPSS rescore
- 2026-09-16 05:15 UTCEPSS rescore
- 2026-09-13 16:47 UTCEPSS rescore
- 2026-09-12 15:01 UTCEPSS rescore
- 2026-09-11 14:52 UTCEPSS rescore
- 2026-09-10 09:34 UTCEPSS rescore
- 2026-09-08 22:00 UTCEPSS rescore
- 2026-09-07 16:01 UTCEPSS rescore
- 2026-09-06 13:47 UTCEPSS rescore
- 2026-09-06 13:47 UTCEPSS rescore
- 2026-09-04 05:06 UTCEPSS rescore
- 2026-09-02 18:08 UTCOSV refresh
- 2026-09-02 14:11 UTCEPSS rescore
- 2026-09-01 13:53 UTCEPSS rescore
- 2026-09-01 04:39 UTCEPSS rescore
- 2026-09-01 04:39 UTCEPSS rescore
- 2026-08-30 19:17 UTCEPSS rescore
- 2026-08-30 01:22 UTCEPSS rescore
- 2026-08-28 21:41 UTCEPSS rescore
- 2026-08-27 14:25 UTCEPSS rescore
- 2026-08-26 14:46 UTCEPSS rescore
- 2026-08-25 13:49 UTCEPSS rescore
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- 2026-08-24 14:17 UTCEPSS rescore
- 2026-08-23 00:19 UTCEPSS rescore
- 2026-08-21 23:49 UTCEPSS rescore
- 2026-08-20 22:55 UTCEPSS rescore
- 2026-08-20 22:55 UTCEPSS rescore
- 2026-08-19 17:03 UTCEPSS rescore
- 2026-08-18 13:48 UTCEPSS rescore
- 2026-08-17 13:47 UTCEPSS rescore
- 2026-08-16 14:56 UTCEPSS rescore
- 2026-08-16 11:14 UTCEG score recompute
- 2026-08-16 02:14 UTCEPSS rescore
- 2026-08-15 01:30 UTCEPSS rescore
- 2026-08-14 07:23 UTCEG score recompute
- 2026-08-13 22:00 UTCEPSS rescore
- 2026-08-12 22:09 UTCEG score recompute
- 2026-08-12 13:50 UTCEPSS rescore
- 2026-08-11 21:30 UTCEG score recompute
- 2026-08-11 04:35 UTCEG score recompute
- 2026-08-11 00:00 UTCEPSS rescore
- 2026-08-09 18:54 UTCEG score recompute
- 2026-08-09 13:46 UTCEPSS rescore
- 2026-08-09 06:57 UTCEG score recompute
- 2026-08-08 16:37 UTCEPSS rescore
- 2026-08-07 17:30 UTCEG score recompute
- 2026-08-06 19:28 UTCEG score recompute
- 2026-08-06 13:46 UTCEPSS rescore
- 2026-08-06 01:37 UTCEG score recompute
- 2026-08-05 19:17 UTCEPSS rescore
- 2026-08-04 15:10 UTCEPSS rescore
- 2026-08-04 10:38 UTCEPSS rescore
- 2026-08-02 16:39 UTCEG score recompute
- 2026-08-02 02:27 UTCEPSS rescore
- 2026-08-01 04:16 UTCEPSS rescore
- 2026-07-30 16:28 UTCEPSS rescore
- 2026-07-30 01:30 UTCEPSS rescore
- 2026-07-28 15:36 UTCEPSS rescore
- 2026-07-27 14:41 UTCEG score recompute
- 2026-07-27 14:27 UTCOSV refresh
Frequently asked(5)
What is CVE-2026-31971?
When was CVE-2026-31971 disclosed?
Is CVE-2026-31971 actively exploited?
What is the CVSS score of CVE-2026-31971?
How do I remediate CVE-2026-31971?
Dependency Blast Radius
See which npm, PyPI, Go, and Maven packages are affected by CVE-2026-31971
Is Your Infrastructure Affected by CVE-2026-31971?
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