CVE-2026-100846

HIGHNVD 8.88.8—
EchelonGraph scoreMEDIUM confidence

This high-severity CVE scores 8.8 under NVD CVSS v3. EPSS exploit probability: 0.3% (19th percentile of EPSS-scored CVEs). GitHub Security Advisory enrichment pending alignment with NVD CVSS.

Triggered by: NVD CVSS baseline
Sources: epss, ghsa, nvd
Trending — 4 sources updated this weekElevated
8.8EG
EchelonGraph verdictPlan a fixSerious severity, but no confirmed exploitation yet.
  • High severity, but no confirmed exploitation yet
CISA-KEV: Not listedEPSS PROB: 0.3%CVSS: 8.8Exploit: Elevated riskExposed services: Not assessed

A fix is available — apply it.

MONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algo_from_pickle function in monai/auto3dseg/utils.py. The function reads a .pkl file and passes its contents to pickle.loads without validating the data source or content. If an application invokes algo_from_pickle on an attacker-supplied pickle file, an object defining __reduce__ is executed during deserialization, resulting in arbitrary code execution in the context of the application.

CVSS v3
8.8
EG Score
8.8HIGHmedium confidence
EG Risk
56
EG Risk 56/100CISA SSVC

EG Risk is EchelonGraph's 0–100 priority score: it fuses intrinsic severity with real-world exploitation and automatability so you can rank equal-severity CVEs and fix the most dangerous first. Higher = act sooner. Distinct from the 0–10 EG Score (severity).

How it’s computed
Severity88% × 45%
Exploitation40% × 40%
Automatability0% × 15%
CISA SSVC: Track at low, Track* at medium and Attend at high mission impact.
Action: A fix is available. Apply it within your standard update timelines at low or medium mission impact and sooner than that at high.
EPSS PROB
0.3%
EPSS %ILE
19th
KEV
Not listed

CISA SSVCTrack at low, Track* at medium and Attend at high mission impact.

A fix is available. Apply it within your standard update timelines at low or medium mission impact and sooner than that at high.

Exploitation public PoC (CISA Vulnrichment) · Automatable no (CISA Vulnrichment) · Technical impact total (CISA Vulnrichment). Mission impact is CISA's Mission & Well-being decision point, and only you can judge it: high means the affected system is essential to your organisation's mission, or its compromise could cause irreversible harm to people. CISA's decision table

Published

September 27, 2026

Last Modified

September 30, 2026

Advisory Details (2)

Auto-updated Sep 27, 2026
🔬 Proof of concept available. Patch available. Sources: github.
generic

MONAI before 1.5.2 Remote Code Execution via Pickle Deserialization | Advisories | VulnCheck

https://www.vulncheck.com/advisories/monai-before-1.5.2-remote-code-execution-via-pickle-deserialization
github Patch Available🟡 PoC Available

Unsafe functions lead to pickle deserialization rce · Advisory · Project-MONAI/MONAI · GitHub

https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-89gg-p5r5-q6r4

Vendor Advisories for CVE-2026-100846(1)

These vendors published their own advisory mentioning this CVE — often with vendor-specific remediation steps + affected product lists not in NVD.

Affected Packages

(1 across 1 ecosystem)
PyPI(1)
PackageVulnerable rangeFixed inDependents
monai0.0.1 ... 1.5.2rc1 (43 versions)1.6.0—

Weakness Classification(1)

MITRE Common Weakness Enumeration — the root-cause categories this CVE belongs to.

Data Freshness Timeline

(refreshed 33× in last 7d / 36× in last 30d)

Each row is a source pipeline that fetched or updated this CVE on that date, with what changed. For example, "NVD update" means NVD published or revised its analysis for this CVE; "MITRE cvelistV5" means we ingested or refreshed it from the CNA feed. Most recent first.

  1. 2026-10-04 09:56 UTCGHSA enrichment
  2. 2026-10-03 21:22 UTCEG score recompute
  3. 2026-10-03 21:22 UTCGHSA enrichment
  4. 2026-10-03 14:25 UTCEPSS rescore
  5. 2026-10-03 08:47 UTCGHSA enrichment
  6. 2026-10-02 20:11 UTCEG score recompute
  7. 2026-10-02 20:11 UTCGHSA enrichment
  8. 2026-10-02 07:34 UTCEG score recompute
  9. 2026-10-02 07:34 UTCGHSA enrichment
  10. 2026-10-01 19:49 UTCEPSS rescore
  11. 2026-10-01 19:00 UTCGHSA enrichment
  12. 2026-10-01 06:21 UTCGHSA enrichment
  13. 2026-09-30 17:47 UTCEG score recompute▲ 1.20
  14. 2026-09-30 17:47 UTCGHSA enrichment
  15. 2026-09-30 17:44 UTCNVD updateCVSS v3 → 8.8
  16. 2026-09-30 16:27 UTCEG score recompute
  17. 2026-09-30 16:27 UTCGHSA enrichment
  18. 2026-09-30 16:05 UTCEG score recompute
  19. 2026-09-30 16:05 UTCGHSA enrichment
  20. 2026-09-30 15:02 UTCEPSS rescore
  21. 2026-09-30 12:21 UTCGHSA enrichment
  22. 2026-09-29 23:47 UTCEG score recompute
  23. 2026-09-29 23:47 UTCGHSA enrichment
  24. 2026-09-29 15:20 UTCEPSS rescore
  25. 2026-09-29 09:47 UTCEG score recompute
Show 11 more
  1. 2026-09-29 09:47 UTCGHSA enrichment
  2. 2026-09-28 21:13 UTCGHSA enrichment
  3. 2026-09-28 16:21 UTCEG score recompute
  4. 2026-09-28 16:21 UTCGHSA enrichment
  5. 2026-09-28 13:50 UTCEPSS rescore
  6. 2026-09-28 03:46 UTCGHSA enrichment
  7. 2026-09-27 15:12 UTCEG score recompute
  8. 2026-09-27 15:12 UTCGHSA enrichment
  9. 2026-09-27 02:36 UTCEG score recompute
  10. 2026-09-27 01:53 UTCEG score recompute
  11. 2026-09-27 01:49 UTCMITRE cvelistV5first tracked

Related CVEs(same product + same CWE)

Frequently asked(5)

What is CVE-2026-100846?
CVE-2026-100846 is a high vulnerability published on September 27, 2026. MONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algofrompickle function in monai/auto3dseg/utils.py. The function reads a .pkl file and passes its contents to pickle.loads without validating the data source or content. If an application invokes algofrompickle on…
When was CVE-2026-100846 disclosed?
CVE-2026-100846 was first published on September 27, 2026, with the most recent update on September 30, 2026. EchelonGraph re-ingests CVE updates from NVD on a 2-hour cycle, so this page reflects the latest published state.
Is CVE-2026-100846 actively exploited?
CVE-2026-100846 is not currently on CISA's Known Exploited Vulnerabilities catalog. FIRST EPSS estimates a 0.3% probability of exploitation in the next 30 days (19th percentile of EPSS-scored CVEs).
What is the CVSS score of CVE-2026-100846?
CVE-2026-100846 has a CVSS v3 base score of 8.8 (NVD).
How do I remediate CVE-2026-100846?
A fix for CVE-2026-100846 is available: update to the fixed version the vendor names in its advisory. The vendor advisories EchelonGraph has for CVE-2026-100846 are linked in the Vendor Advisories panel on this page.

Dependency Blast Radius

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