In MONAI 1.6.0, PersistentDataset (monai/data/dataset.py) explicitly rejects the combination track_meta=True with weights_only=True, forcing users who cache MetaTensors (the default tensor type in MONAI >= 1.0) to run torch.load(hashfile, weights_only=False). Related cache helpers in monai/data/utils.py also call pickle.loads on cached content and derive cache keys with hashlib.md5. As a result, a local user with write access to a shared or world-writable cache_dir (e.g. /tmp/monai_cache, HPC scratch, ~/.cache/monai) can place a malicious pickle file that is deserialized the next time another user's MONAI pipeline reads the cache, resulting in arbitrary code execution in that user's context. All released versions of the monai pip package are affected; no patched version is available as of the advisory.
CVE-2026-100841
Score 7.8 from GitHub Security Advisory (severity: HIGH) published 2026-09-27. A secondary CVSS source baseline 7.8; sources differ by 0.0.
- High severity, but no confirmed exploitation yet
A fix is available — apply it.
- CVSS v3
- 7.8
- EG Score
- 7.8HIGHhigh confidence
- EG Risk
- 35EG Risk 35/100CISA SSVC
EG Risk is EchelonGraph's 0–100 priority score: it fuses intrinsic severity with real-world exploitation and automatability so you can rank equal-severity CVEs and fix the most dangerous first. Higher = act sooner. Distinct from the 0–10 EG Score (severity).
How it’s computedSeverity78% × 45%Exploitation0% × 40%Automatability0% × 15%CISA SSVC: Track at low or medium mission impact; Track* at high (mission-essential systems).Action: A fix is available. Apply it within your standard update timelines. - EPSS PROB
- 0.1%
- EPSS %ILE
- 1st
- KEV
- Not listed
CISA SSVCTrack at low or medium mission impact; Track* at high (mission-essential systems).
A fix is available. Apply it within your standard update timelines.
Exploitation none (CISA Vulnrichment) · Automatable no (CISA Vulnrichment) · Technical impact total (CISA Vulnrichment). Mission impact is CISA's Mission & Well-being decision point, and only you can judge it: high means the affected system is essential to your organisation's mission, or its compromise could cause irreversible harm to people. CISA's decision table
Published
September 27, 2026
Last Modified
September 30, 2026
Advisory Details (2)
Auto-updated Sep 27, 2026MONAI 1.6.0 PersistentDataset Remote Code Execution via Pickle Cache | Advisories | VulnCheck
https://www.vulncheck.com/advisories/monai-1.6.0-persistentdataset-remote-code-execution-via-pickle-cachePersistentDataset forces weights_only=False with MetaTensor + data/utils.py uses pickle.loads/md5 — local-user pickle RCE via shared cache_dir · Advisory · Project-MONAI/MONAI · GitHub
https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-636w-j999-g7x5Vendor Advisories for CVE-2026-100841(1)
These vendors published their own advisory mentioning this CVE — often with vendor-specific remediation steps + affected product lists not in NVD.
Affected Packages
(1 across 1 ecosystem)
PyPI(1)
| Package | Vulnerable range | Fixed in | Dependents |
|---|---|---|---|
| monai | — | — | — |
Weakness Classification(1)
MITRE Common Weakness Enumeration — the root-cause categories this CVE belongs to.
Data Freshness Timeline
(refreshed 34× in last 7d / 39× in last 30d)
Each row is a source pipeline that fetched or updated this CVE on that date, with what changed. For example, "NVD update" means NVD published or revised its analysis for this CVE; "MITRE cvelistV5" means we ingested or refreshed it from the CNA feed. Most recent first.
- 2026-10-04 09:21 UTCGHSA enrichment
- 2026-10-03 22:32 UTCEG score recompute
- 2026-10-03 22:32 UTCGHSA enrichment
- 2026-10-03 14:25 UTCEPSS rescore
- 2026-10-03 11:41 UTCGHSA enrichment
- 2026-10-03 00:33 UTCEG score recompute
- 2026-10-03 00:33 UTCGHSA enrichment
- 2026-10-02 13:44 UTCGHSA enrichment
- 2026-10-02 02:46 UTCEG score recompute
- 2026-10-02 02:45 UTCGHSA enrichment
- 2026-10-01 19:49 UTCEPSS rescore
- 2026-10-01 15:46 UTCGHSA enrichment
- 2026-10-01 04:57 UTCGHSA enrichment
- 2026-09-30 18:07 UTCGHSA enrichment
- 2026-09-30 16:35 UTCEG score recompute
- 2026-09-30 16:35 UTCGHSA enrichment
- 2026-09-30 15:02 UTCEPSS rescore
- 2026-09-30 05:45 UTCGHSA enrichment
- 2026-09-29 18:52 UTCEG score recompute
- 2026-09-29 18:52 UTCGHSA enrichment
- 2026-09-29 15:20 UTCEPSS rescore
- 2026-09-29 08:02 UTCEG score recompute
- 2026-09-29 08:02 UTCGHSA enrichment
- 2026-09-28 21:13 UTCGHSA enrichment
- 2026-09-28 14:26 UTCEG score recompute
Show 14 moreShow fewer
- 2026-09-28 14:26 UTCGHSA enrichment
- 2026-09-28 14:02 UTCEG score recompute
- 2026-09-28 14:02 UTCGHSA enrichment
- 2026-09-28 13:50 UTCEPSS rescore
- 2026-09-28 04:12 UTCGHSA enrichment
- 2026-09-27 17:24 UTCEG score recompute
- 2026-09-27 17:24 UTCGHSA enrichment
- 2026-09-27 16:35 UTCEG score recompute
- 2026-09-27 16:35 UTCGHSA enrichment
- 2026-09-27 13:27 UTCEG score recompute
- 2026-09-27 13:27 UTCGHSA enrichment
- 2026-09-27 02:37 UTCEG score recompute
- 2026-09-27 01:53 UTCEG score recompute
- 2026-09-27 01:49 UTCMITRE cvelistV5first tracked
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Same product
10 shownPyPI:monai
Frequently asked(5)
What is CVE-2026-100841?
When was CVE-2026-100841 disclosed?
Is CVE-2026-100841 actively exploited?
What is the CVSS score of CVE-2026-100841?
How do I remediate CVE-2026-100841?
Dependency Blast Radius
See which npm, PyPI, Go, and Maven packages are affected by CVE-2026-100841
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