CVE-2026-54604

MEDIUMPre-NVD 5.35.3—
EchelonGraph scoreMEDIUM confidence

This medium-severity CVE scores 5.3 under a secondary CVSS source (NVD's own analysis pending). EPSS exploit probability: 0.3%, top 77% of all CVEs by exploit prediction. GitHub Security Advisory data not yet ingested — confidence will rise once GHSA publishes (typical lag: hours to days for open-source ecosystem CVEs; never for infrastructure-only CVEs).

Triggered by: NVD CVSS baseline
Sources: epss, secondary
Trending — 3 sources updated this week
5.3EG
EchelonGraph verdictMonitorLow exploitation likelihood right now — keep watching.
  • Lower severity and no public exploit yet
CISA-KEV: Not listedEPSS PROB: 0%CVSS: 5.3Exploit: None knownExposed: 0

No vendor fix yet — apply a workaround or compensating control (WAF / firewall / segmentation) and watch for a patch.

OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.

CVSS v3
5.3
EG Score
5.3(medium)
EG Risk
24(Track)
EG Risk 24/100SSVC: Track

EG Risk is EchelonGraph's 0–100 priority score: it fuses intrinsic severity with real-world exploitation and automatability so you can rank equal-severity CVEs and fix the most dangerous first. Higher = act sooner. Distinct from the 0–10 EG Score (severity).

How it’s computed
Severity53% × 45%
Exploitation0% × 40%
Automatability0% × 15%
Action: Routine — remediate on your standard cadence.
EPSS PROB
0%
EPSS %ILE
23%
KEV
Not listed

Published

September 17, 2026

Last Modified

September 18, 2026

Advisory Details (7)

Auto-updated Sep 17, 2026
Patch available. Sources: github, github_pr, github_commit, github_release.
generic

`TIFFReadRGBAImageOriented` always places output in bottom left of raster (#791) · Issues · libtiff / libtiff · GitLab

https://gitlab.com/libtiff/libtiff/-/work_items/791
github_release Patch Available

OpenSlide 4.0.1

Patch available: openslide/openslide v4.0.1

https://github.com/openslide/openslide/releases/tag/v4.0.1
github_commit Patch Available

commit a4f0fb0ec462 (openslide/openslide)

Patch available: openslide/openslide v4.0.1 (contains commit a4f0fb0ec462)

https://github.com/openslide/openslide/commit/a4f0fb0ec462edcea97ff22288f606ac6cd370f5
github_pr Patch Available

tiff: fix corrupt non-JPEG partial bottom tile row on libtiff 4.7.1

Patch available: openslide/openslide v4.0.1 (PR #706 merged 2026-03-06)

https://github.com/openslide/openslide/pull/706
github_pr

Fix corrupt partial bottom tile row on non-JPEG, non-JP2K TIFF levels

Fix merged in openslide/openslide-bin PR #436 on 2026-03-09 — awaiting tagged release

https://github.com/openslide/openslide-bin/pull/436
generic

Edge tile corruption in openslide-bin 4.0.0.11 · Issue #433 · openslide/openslide-bin · GitHub

https://github.com/openslide/openslide-bin/issues/433
github Patch Available

openslide_read_region() can return uninitialized memory in OpenSlide < 4.0.1 with libtiff 4.7.1 (CVE-2026-54604) · Advisory · openslide/openslide · GitHub

https://github.com/openslide/openslide/security/advisories/GHSA-f734-jv98-5677

Weakness Classification(2)

MITRE Common Weakness Enumeration — the root-cause categories this CVE belongs to.

Data Freshness Timeline

(refreshed 6× in last 7d / 6× in last 30d)

Each row is a source pipeline that fetched or updated this CVE on that date, with what changed. For example, "NVD update" means NVD published or revised its analysis for this CVE; "MITRE cvelistV5" means we ingested or refreshed it from the CNA feed. Most recent first.

  1. 2026-09-18 20:33 UTCEG score recompute
  2. 2026-09-18 20:10 UTCEG score recompute
  3. 2026-09-18 19:28 UTCEPSS rescore
  4. 2026-09-17 21:20 UTCEG score recompute
  5. 2026-09-17 20:34 UTCEG score recompute
  6. 2026-09-17 20:34 UTCMITRE cvelistV5first tracked

Frequently asked(5)

What is CVE-2026-54604?
CVE-2026-54604 is a medium vulnerability published on September 17, 2026. OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and openslidetiffreadtile() to request a full-height destination for a partial bottom tile row, allowing uninitialized…
When was CVE-2026-54604 disclosed?
CVE-2026-54604 was first published in the National Vulnerability Database on September 17, 2026, with the most recent update on September 18, 2026. EchelonGraph re-ingests CVE updates from NVD on a 2-hour cycle, so this page reflects the latest published state.
Is CVE-2026-54604 actively exploited?
CVE-2026-54604 is not currently on CISA's Known Exploited Vulnerabilities catalog. FIRST EPSS estimates a 0% probability of exploitation in the next 30 days, which ranks it in the top 77.1% of all scored CVEs.
What is the CVSS score of CVE-2026-54604?
CVE-2026-54604 has a CVSS v3 base score of 5.3 (NVD).
How do I remediate CVE-2026-54604?
Patch to the fixed version published by the affected vendor. Where vendor advisories exist for CVE-2026-54604, EchelonGraph cross-links them in the Vendor Advisories panel below — those typically contain the canonical remediation steps, fixed version numbers, and any vendor-specific mitigations.

Dependency Blast Radius

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