CVE-2021-25921

CRITICALNVD 5.49.0▲
EchelonGraph scoreHIGH confidence

Score elevated to 9.0 because EPSS predicts 91% probability of exploitation within the next 30 days (99th percentile of EPSS-scored CVEs). NVD baseline CVSS 5.4 retained for reference. Confidence: see factors.

Triggered by: EPSS exploit prediction ≥85%
Sources: epss, ghsa, nvd
Trending — 3 sources updated this weekWeaponized
9.0EG
EchelonGraph verdictPatch this weekExploitation is likely or a public exploit exists.
  • High exploitation likelihood — EPSS 91%
  • Public exploit code is available (ssvc poc, epss top5pct, epss high)
CISA-KEV: Not listedEPSS PROB: 91%CVSS: 5.4Exploit: ssvc poc · epss top5pct · epss highExposed services: Not assessed

A fix is available — apply it.

In OpenEMR, versions 2.7.3-rc1 to 6.0.0 are vulnerable to Stored Cross-Site-Scripting (XSS) due to user input not being validated properly in the Allergies section. An attacker could lure an admin to enter a malicious payload and by that initiate the exploit.

CVSS v3
5.4
EG Score
9.0CRITICALhigh confidence
EG Risk
77
EG Risk 77/100CISA SSVC

EG Risk is EchelonGraph's 0–100 priority score: it fuses intrinsic severity with real-world exploitation and automatability so you can rank equal-severity CVEs and fix the most dangerous first. Higher = act sooner. Distinct from the 0–10 EG Score (severity).

How it’s computed
Severity90% × 45%
Exploitation91% × 40%
Automatability0% × 15%
CISA SSVC: Track at low or medium mission impact; Track* at high (mission-essential systems).
Action: A fix is available. Apply it within your standard update timelines.
EPSS PROB
91%
EPSS %ILE
99th
KEV
Not listed

CISA SSVCTrack at low or medium mission impact; Track* at high (mission-essential systems).

A fix is available. Apply it within your standard update timelines.

Exploitation public PoC (CISA Vulnrichment) · Automatable no (CISA Vulnrichment) · Technical impact partial (CISA Vulnrichment). Mission impact is CISA's Mission & Well-being decision point, and only you can judge it: high means the affected system is essential to your organisation's mission, or its compromise could cause irreversible harm to people. CISA's decision table

Published

March 22, 2021

Last Modified

April 30, 2025

References (4)

Weakness Classification(1)

MITRE Common Weakness Enumeration — the root-cause categories this CVE belongs to.

Data Freshness Timeline

(refreshed 3× in last 7d / 10× in last 30d)

Each row is a source pipeline that fetched or updated this CVE on that date, with what changed. For example, "NVD update" means NVD published or revised its analysis for this CVE; "MITRE cvelistV5" means we ingested or refreshed it from the CNA feed. Most recent first.

  1. 2026-10-01 19:46 UTCEPSS rescore
  2. 2026-09-30 20:40 UTCOSV refresh
  3. 2026-09-30 15:32 UTCEG score recompute
  4. 2026-09-24 14:00 UTCEPSS rescore
  5. 2026-09-21 20:28 UTCEPSS rescore
  6. 2026-09-19 15:37 UTCEPSS rescore
  7. 2026-09-16 14:05 UTCEPSS rescore
  8. 2026-09-12 14:57 UTCEPSS rescore
  9. 2026-09-12 02:53 UTCOSV refresh
  10. 2026-09-06 13:44 UTCEPSS rescore
  11. 2026-09-05 15:25 UTCEPSS rescore
  12. 2026-08-30 19:14 UTCEPSS rescore
  13. 2026-08-30 01:19 UTCEPSS rescore
  14. 2026-08-28 21:37 UTCEPSS rescore
  15. 2026-08-26 14:42 UTCEPSS rescore
  16. 2026-08-24 14:12 UTCEPSS rescore
  17. 2026-08-24 08:27 UTCOSV refresh
  18. 2026-08-16 14:53 UTCEPSS rescore
  19. 2026-08-16 02:11 UTCEPSS rescore
  20. 2026-08-16 02:11 UTCEPSS rescore
  21. 2026-08-12 13:47 UTCEPSS rescore
  22. 2026-08-08 16:33 UTCEPSS rescore
  23. 2026-08-08 04:49 UTCOSV refresh
  24. 2026-08-05 19:14 UTCEPSS rescore
  25. 2026-07-30 01:28 UTCEPSS rescore
Show 56 more
  1. 2026-07-30 01:27 UTCEPSS rescore
  2. 2026-07-26 14:52 UTCEPSS rescore
  3. 2026-07-26 14:52 UTCEPSS rescore
  4. 2026-07-25 14:15 UTCEPSS rescore
  5. 2026-07-24 14:15 UTCEPSS rescore
  6. 2026-07-23 01:58 UTCEG score recompute
  7. 2026-07-22 21:28 UTCEG score recompute▲ 3.60
  8. 2026-07-22 21:28 UTCGHSA enrichment
  9. 2026-07-22 14:06 UTCEPSS rescore
  10. 2026-07-22 14:06 UTCEPSS rescore
  11. 2026-07-18 23:59 UTCOSV refresh
  12. 2026-07-16 17:00 UTCEPSS rescore
  13. 2026-07-11 08:25 UTCEPSS rescore
  14. 2026-07-11 08:25 UTCEPSS rescore
  15. 2026-07-02 16:57 UTCEPSS rescore
  16. 2026-07-01 06:48 UTCOSV refresh
  17. 2026-06-24 14:03 UTCEPSS rescore
  18. 2026-06-24 14:03 UTCEPSS rescore
  19. 2026-06-23 21:31 UTCEPSS rescore
  20. 2026-06-23 21:31 UTCEPSS rescore
  21. 2026-06-17 17:51 UTCEPSS rescore
  22. 2026-06-15 17:46 UTCEPSS rescore
  23. 2026-06-13 22:58 UTCEPSS rescore
  24. 2026-06-13 22:58 UTCEPSS rescore
  25. 2026-06-13 11:13 UTCOSV refresh
  26. 2026-06-12 23:10 UTCEPSS rescore
  27. 2026-06-11 13:58 UTCEPSS rescore
  28. 2026-06-10 22:16 UTCEPSS rescore
  29. 2026-06-10 13:20 UTCEPSS rescore
  30. 2026-06-08 14:15 UTCEPSS rescore
  31. 2026-06-06 13:46 UTCEPSS rescore
  32. 2026-06-06 13:46 UTCEPSS rescore
  33. 2026-06-06 13:46 UTCEPSS rescore
  34. 2026-06-05 22:45 UTCEPSS rescore
  35. 2026-06-05 22:45 UTCEPSS rescore
  36. 2026-06-05 06:09 UTCEPSS rescore
  37. 2026-06-05 06:09 UTCEPSS rescore
  38. 2026-06-04 13:10 UTCEPSS rescore
  39. 2026-06-04 13:10 UTCEPSS rescore
  40. 2026-06-02 20:11 UTCEPSS rescore
  41. 2026-06-02 20:11 UTCEPSS rescore
  42. 2026-06-02 20:11 UTCEPSS rescore
  43. 2026-06-01 13:50 UTCEPSS rescore
  44. 2026-06-01 13:50 UTCEPSS rescore
  45. 2026-05-31 22:29 UTCEPSS rescore
  46. 2026-05-31 22:29 UTCEPSS rescore
  47. 2026-05-31 00:15 UTCEPSS rescore
  48. 2026-05-29 13:42 UTCEPSS rescore
  49. 2026-05-28 13:43 UTCEPSS rescore
  50. 2026-05-28 13:43 UTCEPSS rescore
  51. 2026-05-27 13:39 UTCEPSS rescore
  52. 2026-05-27 13:39 UTCEPSS rescore
  53. 2026-05-26 19:33 UTCEG score recompute
  54. 2026-05-26 19:33 UTCGHSA enrichment
  55. 2026-05-26 07:17 UTCEPSS rescore
  56. 2026-05-26 07:17 UTCEPSS rescore

Related CVEs(same CWE)

Frequently asked(5)

What is CVE-2021-25921?
CVE-2021-25921 is a critical vulnerability published on March 22, 2021. In OpenEMR, versions 2.7.3-rc1 to 6.0.0 are vulnerable to Stored Cross-Site-Scripting (XSS) due to user input not being validated properly in the Allergies section. An attacker could lure an admin to enter a malicious payload and by that initiate the exploit.
When was CVE-2021-25921 disclosed?
CVE-2021-25921 was first published on March 22, 2021, with the most recent update on April 30, 2025. EchelonGraph re-ingests CVE updates from NVD on a 2-hour cycle, so this page reflects the latest published state.
Is CVE-2021-25921 actively exploited?
CVE-2021-25921 is not currently on CISA's Known Exploited Vulnerabilities catalog. EchelonGraph's EG-KEV model classifies it as weaponized: a functional public exploit exists. FIRST EPSS estimates a 91% probability of exploitation in the next 30 days (99th percentile of EPSS-scored CVEs).
What is the CVSS score of CVE-2021-25921?
CVE-2021-25921 has a CVSS v3 base score of 5.4 (NVD). EchelonGraph synthesises NVD + CISA KEV + FIRST EPSS + GHSA into a combined EG score of 9.0 (CRITICAL).
How do I remediate CVE-2021-25921?
A fix for CVE-2021-25921 is available: update to the fixed version the vendor names in its advisory.

Dependency Blast Radius

Explore the affected products and dependency analysis for CVE-2021-25921

Explore →

Is Your Infrastructure Affected by CVE-2021-25921?

EchelonGraph automatically scans your cloud infrastructure and maps CVE exposure using blast radius analysis.

Book a Demo →Browse All CVEs