On BIG-IP versions 16.0.x before 16.0.1.1, 15.1.x before 15.1.2.1, 14.1.x before 14.1.4, 13.1.x before 13.1.3.6, and 12.1.x before 12.1.5.3, undisclosed requests to a virtual server may be incorrectly handled by the Traffic Management Microkernel (TMM) URI normalization, which may trigger a buffer overflow, resulting in a DoS attack. In certain situations, it may theoretically allow bypass of URL based access control or remote code execution (RCE). Note: Software versions which have reached End of Software Development (EoSD) are not evaluated.
CVE-2021-22991
Score elevated to 9.8 because this CVE is listed on the CISA Known Exploited Vulnerabilities catalog (added 2022-01-18), indicating real-world exploitation has been confirmed by US federal agencies. NVD baseline CVSS 9.8 retained for reference. Confidence: HIGH.
- Actively exploited in the wild (CISA-KEV)
No vendor fix yet — apply a workaround or compensating control (WAF / firewall / segmentation) and watch for a patch.
- CVSS v3
- 9.8
- EG Score
- 9.8(high)
- EG Risk
- 99(Act)EG Risk 99/100SSVC: Act
EG Risk is EchelonGraph's 0–100 priority score: it fuses intrinsic severity with real-world exploitation and automatability so you can rank equal-severity CVEs and fix the most dangerous first. Higher = act sooner. Distinct from the 0–10 EG Score (severity).
How it’s computedSeverity98% × 45%Exploitation100% × 40%Automatability100% × 15%Action: Fix now — active exploitation, automatable, high impact. - EPSS PROB
- 61%
- EPSS %ILE
- 99%
- KEV
- ⚠ Exploited
Published
March 31, 2021
Last Modified
October 27, 2025
Advisory Details (2)
Auto-updated Sep 17, 2026Known Exploited Vulnerabilities Catalog | CISA
Known Exploited Vulnerabilities Catalog | CISA. Listed in CISA Known Exploited Vulnerabilities catalog.
https://www.cisa.gov/known-exploited-vulnerabilities-catalog?field_cve=CVE-2021-22991Weakness Classification(3)
MITRE Common Weakness Enumeration — the root-cause categories this CVE belongs to.
Data Freshness Timeline
(refreshed 52× in last 7d / 225× in last 30d)
Each row is a source pipeline that fetched or updated this CVE on that date, with what changed. For example, "NVD update" means NVD published or revised its analysis for this CVE; "MITRE cvelistV5" means we ingested or refreshed it from the CNA feed. Most recent first.
Showing the most recent 100 of 814 total refreshes for this CVE.
- 2026-09-20 20:00 UTCGHSA enrichment
- 2026-09-20 15:36 UTCGHSA enrichment
- 2026-09-20 11:13 UTCGHSA enrichment
- 2026-09-20 06:49 UTCGHSA enrichment
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- 2026-09-18 23:57 UTCGHSA enrichment
- 2026-09-18 19:34 UTCEG score recompute
- 2026-09-18 19:34 UTCGHSA enrichment
- 2026-09-18 19:23 UTCEPSS rescore
- 2026-09-18 19:20 UTCCISA KEV update
- 2026-09-18 15:10 UTCGHSA enrichment
- 2026-09-18 14:15 UTCCISA KEV update
- 2026-09-18 10:47 UTCGHSA enrichment
- 2026-09-18 06:23 UTCGHSA enrichment
- 2026-09-18 01:59 UTCGHSA enrichment
- 2026-09-17 21:36 UTCEG score recompute
- 2026-09-17 21:36 UTCGHSA enrichment
- 2026-09-17 19:23 UTCEPSS rescore
- 2026-09-17 17:12 UTCGHSA enrichment
- 2026-09-17 12:12 UTCGHSA enrichment
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- 2026-09-17 07:48 UTCGHSA enrichment
- 2026-09-17 03:24 UTCGHSA enrichment
- 2026-09-16 23:00 UTCGHSA enrichment
- 2026-09-16 18:36 UTCGHSA enrichment
- 2026-09-16 14:13 UTCEG score recompute
- 2026-09-16 14:13 UTCGHSA enrichment
- 2026-09-16 14:10 UTCCISA KEV update
- 2026-09-16 14:05 UTCEPSS rescore
- 2026-09-16 14:04 UTCEPSS rescore
- 2026-09-16 09:48 UTCGHSA enrichment
- 2026-09-16 05:24 UTCEG score recompute
- 2026-09-16 05:24 UTCGHSA enrichment
- 2026-09-16 01:01 UTCGHSA enrichment
- 2026-09-15 20:37 UTCGHSA enrichment
- 2026-09-15 16:01 UTCGHSA enrichment
- 2026-09-15 11:36 UTCGHSA enrichment
- 2026-09-15 07:12 UTCEG score recompute
- 2026-09-15 07:12 UTCGHSA enrichment
- 2026-09-15 03:06 UTCEPSS rescore
- 2026-09-15 02:48 UTCGHSA enrichment
- 2026-09-14 22:24 UTCGHSA enrichment
- 2026-09-14 19:24 UTCCISA KEV update
- 2026-09-14 18:00 UTCGHSA enrichment
- 2026-09-14 13:36 UTCGHSA enrichment
- 2026-09-14 09:12 UTCGHSA enrichment
- 2026-09-14 04:48 UTCGHSA enrichment
- 2026-09-14 00:25 UTCGHSA enrichment
- 2026-09-13 20:01 UTCGHSA enrichment
- 2026-09-13 15:37 UTCGHSA enrichment
- 2026-09-13 11:12 UTCGHSA enrichment
- 2026-09-13 06:48 UTCGHSA enrichment
- 2026-09-13 02:19 UTCGHSA enrichment
- 2026-09-12 21:56 UTCGHSA enrichment
- 2026-09-12 17:32 UTCEG score recompute
- 2026-09-12 17:32 UTCGHSA enrichment
- 2026-09-12 14:57 UTCEPSS rescore
- 2026-09-12 13:07 UTCGHSA enrichment
- 2026-09-12 08:43 UTCGHSA enrichment
- 2026-09-12 04:19 UTCGHSA enrichment
- 2026-09-11 23:55 UTCGHSA enrichment
- 2026-09-11 19:31 UTCGHSA enrichment
- 2026-09-11 18:49 UTCCISA KEV update
- 2026-09-11 15:07 UTCEG score recompute
- 2026-09-11 15:07 UTCGHSA enrichment
- 2026-09-11 10:43 UTCEG score recompute
- 2026-09-11 10:43 UTCGHSA enrichment
- 2026-09-11 09:33 UTCEPSS rescore
- 2026-09-11 06:19 UTCGHSA enrichment
- 2026-09-11 01:55 UTCGHSA enrichment
- 2026-09-10 21:31 UTCGHSA enrichment
- 2026-09-10 19:28 UTCCISA KEV update
- 2026-09-10 17:07 UTCGHSA enrichment
- 2026-09-10 12:43 UTCEG score recompute
- 2026-09-10 12:43 UTCGHSA enrichment
- 2026-09-10 09:29 UTCEPSS rescore
- 2026-09-10 08:19 UTCGHSA enrichment
- 2026-09-10 03:55 UTCGHSA enrichment
- 2026-09-09 23:31 UTCGHSA enrichment
- 2026-09-09 19:08 UTCCISA KEV update
- 2026-09-09 19:07 UTCGHSA enrichment
- 2026-09-09 14:43 UTCGHSA enrichment
- 2026-09-09 10:19 UTCGHSA enrichment
- 2026-09-09 05:55 UTCGHSA enrichment
- 2026-09-09 01:32 UTCEG score recompute
- 2026-09-09 01:31 UTCGHSA enrichment
- 2026-09-08 21:56 UTCEPSS rescore
- 2026-09-08 21:08 UTCGHSA enrichment
- 2026-09-08 18:54 UTCCISA KEV update
- 2026-09-08 16:44 UTCGHSA enrichment
- 2026-09-08 12:19 UTCGHSA enrichment
- 2026-09-08 07:52 UTCGHSA enrichment
- 2026-09-08 03:25 UTCGHSA enrichment
- 2026-09-07 23:01 UTCGHSA enrichment
- 2026-09-07 18:37 UTCEG score recompute
- 2026-09-07 18:37 UTCGHSA enrichment
Related CVEs(same CWE)
Same CWE
10 shownCWE-119
Frequently asked(6)
What is CVE-2021-22991?
When was CVE-2021-22991 disclosed?
Is CVE-2021-22991 actively exploited?
What is the CVSS score of CVE-2021-22991?
Which products are affected by CVE-2021-22991?
How do I remediate CVE-2021-22991?
Dependency Blast Radius
Explore the affected products and dependency analysis for CVE-2021-22991
Is Your Infrastructure Affected by CVE-2021-22991?
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