Cytel Studio version 9.0 and earlier is vulnerable to a stack-based buffer overflow triggered by parsing a malformed .CY3 file. The vulnerability occurs when the application copies user-controlled strings into a fixed-size stack buffer (256 bytes) without proper bounds checking. Exploitation allows arbitrary code execution when the crafted file is opened.
CVE-2011-10015
This critical-severity CVE scores 9.3 under NVD CVSS v3. EPSS exploit probability: 4.2%, top 11% of all CVEs by exploit prediction. GitHub Security Advisory data not yet ingested — confidence will rise once GHSA publishes (typical lag: hours to days for open-source ecosystem CVEs; never for infrastructure-only CVEs).
- High severity, but no confirmed exploitation yet
No vendor fix yet — apply a workaround or compensating control (WAF / firewall / segmentation) and watch for a patch.
- CVSS v3
- 9.3
- EG Score
- 9.3(medium)
- EPSS
- 32.2%
- KEV
- Not listed
Published
August 13, 2025
Last Modified
May 25, 2026
Advisory Details (6)
Auto-updated Jun 10, 2026Cytel Studio <= 9.0 .CY3 File Stack Buffer Overflow | Advisories | VulnCheck
https://www.vulncheck.com/advisories/cytel-studio-cy3-file-stack-buffer-overflowWayback Machine
https://web.archive.org/web/20110301000000*/http://www.cytel.com/Software/StatXact.aspxCytel, Inc. Adaptive Clinical Trial Software and Statistical Applications - SiZ, East, StatXact, LogXact
https://web.archive.org/web/20110708215830/http://www.cytel.com/Software/StatXact.aspxCytel, Inc. Adaptive Clinical Trial Software and Statistical Applications - SiZ, East, StatXact, LogXact
https://web.archive.org/web/20110708215826/http://www.cytel.com/Software/LogXact.aspxWeakness Classification(1)
MITRE Common Weakness Enumeration — the root-cause categories this CVE belongs to.
Data Freshness Timeline
(refreshed 8× in last 7d / 43× in last 30d)
Each row is a source pipeline that fetched or updated this CVE on that date, with what changed. For example, "NVD update" means NVD published or revised its analysis for this CVE; "MITRE cvelistV5" means we ingested or refreshed it from the CNA feed. Most recent first.
- 2026-07-11 08:22 UTCEPSS rescore
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- 2026-06-22 14:22 UTCEPSS rescore
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- 2026-06-08 15:45 UTCEG score recompute▲ 9.30
- 2026-06-08 15:45 UTCGHSA enrichment
- 2026-06-07 15:22 UTCEPSS rescore
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- 2026-06-06 13:45 UTCEPSS rescore
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- 2026-05-22 21:15 UTCEPSS rescore
- 2026-05-22 21:15 UTCEPSS rescore
- 2026-05-22 21:15 UTCEPSS rescore
- 2026-05-21 09:58 UTCEG score recompute
- 2026-05-21 09:58 UTCGHSA enrichment
- 2026-05-20 22:37 UTCEPSS rescore
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- 2026-05-18 21:29 UTCEPSS rescore
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Publicly available exploits
(1 reference)Working exploit code is in the public domain (1 Metasploit module). Defenders should treat patch urgency accordingly — public PoCs typically lead to mass-exploitation within 24-72 hours.
- Metasploitexploit/windows/fileformat/cytel_studio_cy3✓ verifiedFirst seen Oct 2, 2011
Cytel Studio 9.0 (CY3 File) Stack Buffer Overflow
Open source ↗
Related CVEs(same CWE)
Same CWE
10 shownCWE-121
- CVE-2012-10058EG 10.0CRITICAL
- CVE-2010-20113EG 9.8CRITICAL
- CVE-2010-20121EG 9.8CRITICAL
- CVE-2012-10060EG 9.8CRITICAL
- CVE-2012-10023EG 9.8CRITICAL
- CVE-2013-10042EG 9.8CRITICAL
- CVE-2012-10021EG 9.8CRITICAL
- CVE-2014-125117EG 9.8EPSS 91%CRITICAL
- CVE-2017-14854NVD 9.1EG 9.8EPSS 94%CRITICAL
- CVE-2015-1006EG 9.8EPSS 92%CRITICAL
Frequently asked(5)
What is CVE-2011-10015?
When was CVE-2011-10015 disclosed?
Is CVE-2011-10015 actively exploited?
What is the CVSS score of CVE-2011-10015?
How do I remediate CVE-2011-10015?
Dependency Blast Radius
Explore the affected products and dependency analysis for CVE-2011-10015
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